Bioinstrumentation and Nanomedicine

11-1bioinstrumentation
From left to right: Nazaríao Féliz, Flavio Vinicio Changoluisa, Alfonso Muinelo, Ana Lorena Urbano, Rodolfo Maestre, Javier Serrano, Cristina Sánchez, Jorge Díaz Mateus.

Target: Development of new instruments and medical devices for research purposes and for clinical and/or domestic use. We focus on the design of equipment and prototype building and validation, so that we always follow our project and research lines in strong collaboration with the final users, normally physicians and biologists.

Description: The LBN is formed by the Platform for Functional Characterization of Nanoparticles (a CIBER-BBN facility), the Bioinstrumentation Unit (BU) and the Nanomedicine Unit (NU). The Platform performs analysis on the behaviour of nanoparticles that can be used, for instance, as hyperthermia agents, contrast agents for MRI and magnetic materials. In the BU we develop prototypes for new instruments including all the electronics, the informatics and biochemical aspects. The NU is primarily devoted to research activities and it is a broader concept than the other units since it includes the collaborations among three different laboratories: the Nanotechnology Laboratory for the development of nanomaterials, the Biology and Biofunctionalization Laboratory for the biological assays and the LBN for the development of instrumentation and validation of the results.

Techniques: Optical Hyperthermia. Magnetic Hyperthermia. Ultra sensible Magnetrometry. Relaxometer. Mechanical characterization of magnetic nanoparticles. Guidance and focusing of magnetic nanoparticles. Production of water based viscosity-controlled fluids. Blood phantom for mechanical properties. Interstitial fluid phantom for optical properties.

Infrastructure: Electronic set-up for circuits design and checking, including microwaves, ultrasound set-up, pptical set-up for guided light, fast field cycling magnetometer, alternating gradient field magnetometer, permanent magnet of 0.4 T and 100 cm2 homogeneous field (MRI compatible).

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