Experimental neurology

The Experimental Neurology Unit is focused on understanding the pathophysiological mechanisms
of a variety of neurological disorders, searching for therapeutic and early diagnostic opportunities.

Our research lines have a double aspect, basic and applied. Main research areas are the following:

● Advanced therapies in cerebrovascular diseases and neurodegenerative disorders.
● Biomarkers for early diagnosis in cerebral pathologies.
● Hyperthermic therapy and gold nanorods and magnetic nanoparticles for cell death induction in glioblastoma.
● Interaction between electromagnetic fields and biological systems.
● Electromagnetic field personnel dosimetry and environmental dosimetry in urban environments.
● Biomarkers of tumor-initiating cells with computational analysis aimed at the design of relapse prediction algorithms in advanced neoplastic disease.
● Dose-response assays in xenograft models derived from tumor-initiating cells from patients with advanced neoplastic disease.
● Synergy studies of self-renewing proteins (PEDF) with antioxidant activities and anti-neoplastic drugs, and subsequent control of molecular expression of their signaling pathways.

MAIN LABORATORIES:

Bioelectromagnetism (Ceferino Maestú)
Molecular Biology (Milagros Ramos)
Cancer Stem Cell (Carmez Ramirez-Castillejo, http://csc.ctb.upm.es/ )
Experimental Neurology (Daniel González-Nieto, http://www.exp-neurolab.org/ )